If Statement Efficiency Help

ok, so I have an if statement that is huge :

if( slotNo[0] == 1 && slotNo[1] != 1 && slotNo[2] != 1 && slotNo[3] != 1 && slotNo[4] != 1 && slotNo[5] != 1)
		{
			winnings = 2;
		}

and I would like to know if there is a more efficient way of doing this if statement. I don’t even know how reliable that statement is.

My if statements are gonna get worse too, because I’m going to have a lot of or’s and ands to check.

So if anyone has any advice on how I could do this more reliably and more efficiently would be very appreciated.